Clinical Chemistry - CK-MB

CK-MB is a more sensitive marker to myocardial infarction than total CK activity as CK-MB has a lower basal level and a narrower normal range. In the vast majority of cases the CK-MB activity rises within 4 to 6 hours of an acute infarction. Between 10 to 24 hours, maximum values are observed. The CK-MB activity generally returns to normal between the third and fourth day post- infarction.

The Randox CK-MB reagent can measure small, but significant changes in CK-MB activity during the early hours following the onset of chest pain.