Specific Proteins - IgE

Continual production of IgE antibodies in response to common naturally occurring allergens and the production of excessive amounts of histamine by the IgE bound mast cells results in the development of such clinically important allergic reactions such as asthma, hay fever, dermatitis and food allergies. Elevated IgE levels are also seen in parasitic diseases, IgE myeloma and in hepatitis.

The Randox IgE assay is an immunoturbidimetric end-point method for automated analysers. The increase in turbidity in a sample containing human IgE is measured at 570 nm. The absorbance change is proportional to the quantity of IgE in the sample.