Specific Proteins - IgA

Measurement of IgA is used to diagnose diseases of the respiratory tract e.g. tuberculosis, Crohn’s disease and early cirrhosis of the liver. It is also useful in monitoring therapy of IgA myeloma and evaluating IgA immunity. IgA in colostrum and milk is important in neonatal defence against infection.

The Randox IgA assay is an immunoturbidimetric end-point method for manual use and on automated analysers. The increase in turbidity in a sample containing human IgA is measured at 340 nm. By constructing a standard curve from the absorbances of standards, the IgA concentration of a sample can be determined.